CMB-OV | Cancer Moonshot Biobank - Ovarian Carcinoma Cancer Collection
DOI: 10.7937/4nx6-e061 | Data Citation Required | 452 Views | Image Collection
| Location | Species | Subjects | Data Types | Cancer Types | Size | Status | Updated | |
|---|---|---|---|---|---|---|---|---|
| Ovary | Human | 14 | Histopathology | Ovarian Cancer | Clinical | Public, Ongoing | 2024/08/28 |
Summary
The Cancer Moonshot Biobank is a National Cancer Institute initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens (blood and tissue removed during medical procedures) and associated data will be collected longitudinally from at least 1000 patients across at least 10 cancer types, who represent the demographic diversity of the U.S. and receiving standard of care cancer treatment at multiple NCI Community Oncology Research Program (NCORP) sites. This collection contains de-identified radiology and histopathology imaging procured from subjects in NCI’s Cancer Moonshot Biobank - Ovarian Carcinoma Cancer (CMB-OV) cohort. Associated genomic, phenotypic and clinical data will be hosted by The Database of Genotypes and Phenotypes (dbGaP) and other NCI databases. A summary of Cancer Moonshot Biobank imaging efforts can be found on the Cancer Moonshot Biobank Imaging page.
Data Access
Version 1: Updated 2024/08/28
| Title | Data Type | Format | Access Points | Subjects | License | |||
|---|---|---|---|---|---|---|---|---|
| Tissue Slide Images, Pathology Metadata | Histopathology | SVS and JSON | Download requires IBM-Aspera-Connect plugin |
14 | 27 | CC BY 4.0 |
Additional Resources for this Dataset
The database of Genotypes and Phenotypes (dbGaP) hosts genomic, phenotypic, and clinical data for NCI’s Cancer Moonshot Biobank (CMB) project. Information and access to the data can be found at:
- dbGaP – Cancer Moonshot Biobank (Genomic, Phenotypic & complete Clinical Data – controlled access)
- CTDC – Cancer Moonshot Biobank (subset of Clinical Data – open access)
Citations & Data Usage Policy
Data Citation Required: Users must abide by the TCIA Data Usage Policy and Restrictions. Attribution must include the following citation, including the Digital Object Identifier:
Data Citation |
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Cancer Moonshot Biobank. (2024). Cancer Moonshot Biobank – Ovarian Carcinoma Cancer Collection (CMB-OV) (Version 1) [dataset]. The Cancer Imaging Archive. https://doi.org/10.7937/4nx6-e061 |
Acknowledgement |
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The Cancer Moonshot Biobank program requests that publications using data from this program include the following statement: “Data used in this publication were generated by the National Cancer Institute’s Cancer Moonshot Biobank.” |
Detailed Description
Introduction
Biobank radiology imaging data on TCIA contains the “days from enrollment (registration)” for each scan, embedded in the DICOM files (DICOM tag (0012,0053)). This allows for temporal alignment between the imaging on TCIA and clinical events data found on the Biobank Catalog.
Note: In order that the images display properly in DICOM readers, the radiology imaging data also contains de-identified dates that preserve the temporal sequence relationship between scans in a given study.
Days from enrollment (registration)
In addition to modifying the actual date fields in the DICOM header, the “days from registration” values are calculated and stored in the DICOM tag (0012,0052) Longitudinal Temporal Offset from Event with the associated tag (0012,0053) Longitudinal Temporal Event Type set to “REGISTRATION”. Here is an example DICOM header from a scan where the patient’s imaging was performed 2 days before the registration, resulting in a negative offset value.
| (0012,0052) | Longitudinal Temporal Offset from Event | -2.0 |
| (0012,0053) | Longitudinal Temporal Event Type | REGISTRATION |
If you would like to filter your search results using this information, you can leverage the “Clinical Trial Time Points” filter via our data portal at https://nbia.cancerimagingarchive.net/nbia-search/.
De-identification of DICOM dates
De-identification of dates for this dataset uses the DICOM Part 3.15 Annex E standard “Retain Longitudinal With Modified Dates Option” which allows dates to be retained as long as they are modified from the original date. TCIA implements this using a technique which de-identifies the dates while preserving the longitudinal relationship between them. Original dates will be first normalized to January 1, 1960 and then offset relative to the date of registration for each patient. This normalized date system was chosen in order to make it obvious that the dates are not real, and to make it easy to quickly determine how much time has passed between the date of registration and the patients’ related imaging studies.
For example, if the real date of a patient’s registration was 03/27/2018 and the original imaging Study Date was 03/29/2018 then the anonymized TCIA Study Date would become 01/03/1960 (two days after the base date of 1/1/1960).
Related Publications
Publications by the Dataset Authors
The authors recommended the following as the best source of additional information about this dataset:
No other publications were recommended by dataset authors.
Research Community Publications
TCIA maintains a list of publications that leveraged this dataset. If you have a manuscript you’d like to add please contact TCIA’s Helpdesk.