In our study, we have generated proteomic and genomic (RNA sequencing and whole genome sequencing) profiles from high grade serous ovarian cancer (HGSOC) tumor biopsies. All biospecimens are formalin-fixed, parrafin-embedded (FFPE) tissues and annotated for patient sensitivity to platinum chemotherapy (refractory or sensitive). For all 174 tumors that were analyzed, we have H&E-stained and imaged the first and...
This dataset was derived from tracked biopsy sessions using the Artemis biopsy system, many of which included image fusion with MRI targets. Patients received...
This collection of prostate Magnetic Resonance Images (MRIs) was obtained with an endorectal and phased array surface coil at 3T (Philips Achieva). Each patient had biopsy confirmation of cancer and underwent a robotic-assisted radical prostatectomy. A mold was generated from each MRI, and the prostatectomy specimen was first placed in the mold, then cut in the same plane as the MRI. The data was generated at the National...
Prostate cancer T1- and T2-weighted magnetic resonance images (MRIs) were acquired on a 1.5 T Philips Achieva by combined surface and endorectal coil, including dynamic contrast-enhanced images obtained prior to, during and after I.V. administration of 0.1 mmol/kg body weight of Gadolinium-DTPA (pentetic acid). Corresponding clinical metadata (XLS format) and 3D segmentation files (NRRD format) are offered as a supplement...
This collection consists of DICOM images and DICOM Segmentation Objects (DSOs) for 197 patients with Colorectal Liver Metastases (CRLM). The collection consists of a large, single-institution consecutive series of patients that underwent resection of CRLM and matched preoperative computed tomography (CT) scans for quantitative image analysis. Inclusion criteria were (a) pathologically confirmed resected CRLM, (b) available...
Clinically effective methods to predict the efficacy of sunitinib, for patients with metastatic or locally advanced pancreatic neuroendocrine tumors (panNET) are scarce, making precision treatment difficult. This study aimed to develop and validate a computed tomography (CT)-based method to predict the efficacy of sunitinib in patients with panNET.
Pretreatment CT images of 171 lesions from 38 patients with panNET...
As part of a more general effort to probe the interrelated factors impacting the accuracy and precision of lung nodule size estimation, we have been conducting phantom CT studies with an anthropomorphic thoracic phantom containing a vasculature insert on which synthetic nodules were inserted or attached.
The utilization of synthetic nodules with known truth regarding size and location allows for bias and variance...
Purpose: Expert selected landmark points on clinical image pairs provide a basis for rigid registration validation. Using combinatorial rigid registration optimization (CORRO) we provide a statistically characterized reference data set for image registration of the pelvis by estimating the optimal ground truth.
Methods: Landmark points for each CT/CBCT image pair for 58 pelvic cases...
This dataset was collected by a collaboration of researchers from Children’s Wisconsin, Marquette University, Varian Medical Systems, Medical College of Wisconsin, and Stanford University as part of a project funded by the National Institute of Biomedical Imaging and Bioengineering (U01EB023822) to develop tools for rapid, patient-specific CT organ dose estimation. The collection consists of CT images in DICOM format...
