This collection contains data from the Children’s Oncology Group (COG) Clinical Trial NCT00945009, “Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor, " Study Chair: Peter F. Ehrlich, M.D. M.S.C. It was sponsored by NCI and performed by the Children's Oncology Group under study number AREN0534. This phase III trial studies...
This collection contains data from the Children’s Oncology Group (COG) Clinical Trial NCT01026220, “Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma". Principal Investigator: Kara Kelly, MD (pediatric oncologist and the Chair of Roswell Park Oishei Children’s Cancer and Blood Disorders...
Acute lymphoblastic leukemia (ALL) constitutes approximately 25% of the pediatric cancers. In general, the task of identifying immature leukemic blasts from normal cells under the microscope is challenging because morphologically the images of the two cells appear similar.
Train set composition:
Total subjects:...
Radiology imaging is playing an increasingly vital role in the diagnosis of COVID-19 patients and determining therapeutic options, patient care management and new research directions. Publicly available imaging data is essential to drive new research by permitting the creation of large multi-site cohorts for machine learning based analyses. All too frequently rural populations are underrepresented in such public...
This collection contains data from the Children’s Oncology Group (COG) Clinical Trial NCT00392327, "Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET". The Study Chair was James M. Olson, M.D., Ph.D. It was sponsored by NCI and performed by the Children's Oncology Group...
Background: The functional and biological properties of the tumor microenvironment are fundamentally important determinants of tumor response and therapy outcome in cancer. Oxygenation status and vascularity are known to influence radiation response, and molecular energy metabolism and proliferation, modulate risk of disease recurrence and metastatic progression. However, with the...
Deep learning (DL) has a promising potential in reducing the workload of radiologists and helping them provide a more accurate diagnosis. However, fully annotated and large-sized datasets are required. This dataset is a collection of 2,006 high-resolution Contrast-enhanced spectral mammography (CESM) images with annotations and medical reports.
CESM is done using...
Sporadic gliomas in companion dogs provide a window on the interaction between tumorigenic mechanisms and host environment. We compared the molecular profiles of canine gliomas with those of human pediatric and adult gliomas to characterize evolutionarily conserved mammalian mutational processes in gliomagenesis. Employing whole genome-, exome-, transcriptome- and methylation-sequencing of 81 canine gliomas, our cross-species...
We present a large-scale dataset of 350 histologic samples of seven different canine cutaneous tumors. All samples were obtained through surgical resection due to neoplastic indicators and were selected retrospectively from the biopsy archive of the Institute for Veterinary Pathology of the Freie Universität Berlin according to sufficient tissue preservation and presence of characteristic histologic features for the...
The Cancer Moonshot Biobank is a National Cancer Institute initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens...
